Our research focuses on using long-term monitoring of circadian rhythms in chronic illness diagnosis management. Our main field of medicine is psychiatry, where we search through data for factors indicating recurrent flare-ups of psychiatric conditions, particularly mood disorders and psychoses.
However, we are also involved in research in other fields of medicine:
One of the main indicators we use is sleep. In order to obtain as accurate sleep data from users as possible we have our detection algorithms regularly validated in sleep laboratories against polysomnographs. In addition, our partnership with the SleepAsAndroid application gives us access to an anonymous database of more than 10 million sleep records, which we use as a benchmark for the population.
Are you a researcher? Interested in using the Mindpax system?
Analysis of actigraph parameters for relapse prediction in bipolar disorder: a feasibility study. Novák D., Albert F., Španiel F.; Conf Proc IEEE Eng Med Biol Soc. 2014
Effectiveness of the information technology-aided program of relapse prevention in schizophrenia (ITAREPS): a randomized, controlled, double-blind study. Španiel F., Hrdlička J., Novák T., Kožený J., Höschl C., Mohr P., Motlová. J.; Psychiatr Pract. 2012
ITAREPS: information technology aided relapse prevention programme in schizophrenia. Spaniel F., Vohlídka P., Hrdlicka J., Kozený J., Novák T., Motlová L., Cermák J., Bednarík J., Novák D. Höschl C.; Schizophr Res. 2008
Technical specifications of Mindpax system
Mindpax validation study against MotionWatch
Actigraphic features of bipolar disorder: a systematic review and meta-analysis. Sleep Medicine Reviews. De Crescenzo, F., Economou, A., Sharpley, A. L., Gormez, A., & Quested, D.J., 3. 5. 2016
Delayed sleep phase in young people with unipolar or bipolar affective disorders. Journal of Affective Disorders, 145(2), 260–263. Robillard, R., Naismith, S. L., Rogers, N. L., Ip, T. K. C., Hermens, D. F., Scott, E. M., & Hickie, I. B. , 6. 6. 2012,www.jad-journal.com/article/
Nonparametric methods in actigraphy: An update. Sleep Science, 7(3), 158–164. Gonzalves, B. S. B., Cavalcanti, P. R. A., Tavares, G. R., Campos, T. F., & Araujo, J. F., 13. 9. 2014, www.sciencedirect.com/science/article
Circadian activity rhythm abnormalities in ill and recovered bipolar I disorder patients. Bipolar Disorders, 10(2), 256–265. Salvatore, P., Ghidini, S., Zita, G., De Panfilis, C., Lambertino, S., Maggini, C., & Baldessarini, R. J. , 5. 5. 2007, onlinelibrary.wiley.com
For more information on the effects of circadian rhythms and sleep
on your health see the section on biorhythms.