Long-term monitoring of circadian rhythms

Our research focuses on using long-term monitoring of circadian rhythms for managing chronic illness diagnoses. Our main field of medicine is psychiatry, where we examine data for factors indicating recurrent flare-ups of certain psychiatric conditions, particularly mood disorders and psychoses.

However, we are also involved in research in other fields of medicine:

  • somnology
  • neurology
  • pneumology.
  • Sleep as the main indicator

    One of the main indicators we use is sleep. In order to obtain the most accurate sleep data from users as possible, we have our detection algorithms regularly validated in sleep laboratories against polysomnographs. In addition, our partnership with the SleepAsAndroid application gives us access to an anonymous database of more than 10 million sleep records, which we use as a benchmark for the population.


    Are you a researcher? Interested in using the Mindpax system?

    Examples of published research papers

    Analysis of actigraph parameters for relapse prediction in bipolar disorder: a feasibility study. Novák D., Albert F., Španiel F.; Conf Proc IEEE Eng Med Biol Soc. 2014

    Effectiveness of the information technology-aided program of relapse prevention in schizophrenia (ITAREPS): a randomized, controlled, double-blind study. Španiel F., Hrdlička J., Novák T., Kožený J., Höschl C., Mohr P., Motlová. J.; Psychiatr Pract. 2012 

    ITAREPS: information technology aided relapse prevention programme in schizophrenia. Španiel F., Vohlídka P., Hrdlička J., Kožený J., Novák T., Motlová L., Čermák J., Bednařík J., Novák D., Höschl C.; Schizophr Res. 2008 

    Factsheets – download factsheets to get more information about Mindpax

    Technical specifications of Mindpax system

    Mindpax validation study against MotionWatch

    Examples of third party research in the field

    Actigraphic features of bipolar disorder: a systematic review and meta-analysis. Sleep Medicine Reviews. De Crescenzo, F., Economou, A., Sharpley, A. L., Gormez, A., & Quested, D.J., 3. 5. 2016

    Delayed sleep phase in young people with unipolar or bipolar affective disorders. Journal of Affective Disorders, 145(2), 260–263. Robillard, R., Naismith, S. L., Rogers, N. L., Ip, T. K. C., Hermens, D. F., Scott, E. M., Hickie, I. B., 6. 6. 2012, www.jad-journal.com/article/

    Nonparametric methods in actigraphy: An update. Sleep Science, 7(3), 158–164. Gonzalves, B. S. B., Cavalcanti, P. R. A., Tavares, G. R., Campos, T. F., Araujo, J. F., 13. 9. 2014,  www.sciencedirect.com/science/article

    Circadian activity rhythm abnormalities in ill and recovered bipolar I disorder patients. Bipolar Disorders, 10(2), 256–265. Salvatore, P., Ghidini, S., Zita, G., De Panfilis, C., Lambertino, S., Maggini, C., & Baldessarini, R. J. , 5. 5. 2007, onlinelibrary.wiley.com

    For more information on the effects of circadian rhythms and sleep
    on your health see the section on biorhythms.